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Cholez et al

hepatic macrophages, Kupffer cells, hepatic neutrophils, produce and release large quantities of ROS such as superoxide anion, hydrogen peroxide, nitric oxide, and their derivatives, which target the surrounding tissue and cause oxidative stress intra- or extracelluarly (Bautista et al

& Smidt, M

Figure 4C illustrates the shortest pathway through which polyphenolic compounds Gallic acid, Myricetin, Quercetin, Apigenin, and Kaempferol interact with key molecular targets, Hydroxysteroid 17Beta Dehydrogenase 10 (HSD17B10) and Transthyretin (TTR), to exert their therapeutic effects

4A) was decreased and E-cadherin expression (representative images in Fig