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C57BL/6 J young mice (males, 8 weeks) and aged mice (males, 16 month) were used to generate the pulmonary fibrosis model

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, myeloperoxidase, leukotriene B4, tromboxane B2) (44), interacts with prostaglandin-dependent pathways (45, 46), has a direct protective and proliferative effect on target cells (18, 19), and modulates the release of nitric oxide (27)
