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6e, f, and Supplementary Fig
In addition, we have found evidence by conducting cellular-level studies and using animal models that the process of iron chelation can be used to effectively maintain joint homeostasis
These findings indicate that global downregulation of Nrf2 targets and other antioxidant genes, and decreased glutathione and NADPH act to impair persister cell lipid peroxidation defense and contribute to a dependence on GPX4 for survival
HEL-S-122m UniProt ID: (Human) P00390 Entrez Gene ID: (Human) 2936
These findings collectively suggest that -EC is bioavailable and may serve as a potential therapeutic agent
