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Intervertebral disc diseases part 2: a review of the current diagnostic and treatment strategies for intervertebral disc disease

Kotsafti A, Scarpa M, Castagliuolo I, Scarpa M

A sixth ligand, possibly a hydroxide ion, also participates in stabilizing the Mn 2+ conformation and facilitating the next catalytic round

Triggered by reactive oxygen species (ROS), the process begins with hydrogen abstraction from bis-allylic methylene groups, producing lipid radicals that react with molecular oxygen to form lipid peroxyl radicals
