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An acute SLAP injury may result from: A motor vehicle collision A fall onto an outstretched arm Forceful pulling on the arm, such as when trying to catch a heavy object Rapid or forceful movement of the arm when it is above the level of the shoulder Shoulder dislocation People who participate in repetitive overhead sports, such as throwing athletes or weightlifters, can experience labrum tears as a result of repeated shoulder motion

Lyophilized powder lasts 2-3 years when refrigerated

2003 Jan 1;16(1):47-57

While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51

The transcriptional regulator NF-B plays a pivotal role in inflammation owing to its ability to induce the transcription of an array of inflammatory genes, especially those involved in the regulation of pro-inflammatory molecules [31]