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7 Treatment Given the occurrence of immune exhaustion in these viral infection-related syndromes, one might think that the use of ICI, such as anti-PD1 and anti-CTLA4 antibodies, could be helpful in reactivating the immune system, but these antibodies may not be beneficial in this specific context (231)
When 24-hour urine collection occurs, the total volume is important to record

doi: 10.1017/S1461145705005791 186 HollanderEChaplinWSooryaLWassermanSNovotnySRusoffJet al

This gives you 2.5 total doses at 2mg each, which means the 5mg vial works best for starting dose weeks

This subsequently upregulates expression of the pro-apoptotic transcription factors ATF4/CHOP
