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Description
While some contributing factors to ADA formation are known, the molecular mechanisms of how therapeutic mAbs elicit ADAs are not completely clear
As a catechin compound, EGCG simultaneously inhibits COX2 by suppressing NFB activation in HeLa and SiHa cells while regulating ROS levels, suggesting its antitumor effects may operate through antioxidant pathways [118]
There are no validated human protocols
Rodriguez-Rojas, Rafael
After incubation, cells were lysed using the Promega caspase 3/7 Glo kit and the intensity ofcaspase3/7 were read using Perkin-Elmer Enspire plate reader
