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B., Chen, X

doi: 10.3389/fonc.2020.00085 119 TaylorB

For the nanoprecipitation method, PLGA polymer was dissolved in a suspension of DDA-GSH-AuNCs in dichloromethane (DCM) (after the phase transfer) and the resulting mixture was added drop wise into ethanol (non-solvent for PLGA and non-suspending medium for DDA-GSH-AuNCs) resulting in the formation of PLGA nanoparticles loaded with DDA-GSH-AuNCs (cartoon for the encapsulation process is sketched in Fig

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The issue is usually temporary and not severe enough to become problematic
