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Glutathione is a potent antioxidant naturally produced in the body, composed of the amino acids cysteine, glutamine, and glycine
When chronic pancreatitis is related to alcoholism, the concentration of insoluble proteins increases in the pancreatic secretions

Feb 1 2019;100(2):305-317

Induction of NQO1 by SFN also coordinately induces [58] genes encoding cellular NADPH-regenerating enzymes such as glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and malic enzyme

In the SLC7A11 systemic knockout mouse model, depletion of GSH levels was observed, but did not cause spontaneous hepatic iron deficiency, but rather increased sensitivity to ferroptosis [52]
