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HgbA1c levels significantly declined (p = 0.02) in the NAC group versus the control that was not changed and the levels were significantly less (p = 0.028) in the NAC versus controls at the end of the study, Fig
Furthermore, a previous study showed that as a close structural analogue of L -tyrosine, L -DOPA can be incorporated into synthesized proteins, leading to protein misfolding and inactivation in SH-SY5Y neuroblastoma cells [117]
In an in vitro model of Erastin-induced ferroptosis in PC12 neuronal cells, the iron inhibitor curcuminpolydopamine nanoparticles (Cur-PDA NPs) markedly enhanced the chelation of Fe 3+ and Fe 2+ , upregulated superoxide dismutase (SOD) and GSH expression, reduced Fe 2+ and ROS levels, inhibited lipid peroxidation, restored mitochondrial function, and attenuated neuronal ferroptosis
Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
Infratentorial lesions predict long-term disability in patients with initial findings suggestive of multiple sclerosis
