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Despite the small size of the tri- and tetrapeptides, a property ultimately necessary for BBB permeability, these molecules were metabolically unstable and likely too hydrophilic to breach the BBB

PLoS ONE 10(6):e0128663
Calms &

Cellular receptors and signaling pathways in ocular tissues Vision peptides exert effects by binding specific receptors triggering intracellular signaling cascades
