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& Rozen, R

Driven by the need to estimate internal exposures where in vivo data generation is not possible, alternative testing strategies incorporating in vitro and in silico human specific models have recently gained interest
Keloids result from excessive collagen production driven by myofibroblasts

10.1007/s12035-022-02847-x 128

These effects represent nutrient (amino acid) deprivation, an event that in turn activates another eIF-2 kinase, GCN2
