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The injection might cause a brief pinch or discomfort, but it is generally well-tolerated

10.1007/978-0-85729-923-9_31 Pediatric Critical Care Study Guide 11 GaoY.-Y.ZhangZ.-H.ZhuangZ.LuY.WuL.-Y.YeZ.et al (2018)

It depends on how bad the deficiency is and how well you respond

Subiran N, Pinto FM, Agirregoitia E, Candenas L, Irazusta J