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This is predominantly due to sulfites which are compounds that can cause headaches, flushing, and fatigue

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Panizzutti B., Bortolasci C., Hasebe K., Kidnapillai S., Gray L., Walder K., Berk M., Mohebbi M., Dodd S., Gama C., et al

When to Consider Detox Supplements Targeted detox supplements are most appropriate when you experience several persistent symptoms after ruling out other medical causes, when your occupation or environment involves above-average toxin exposure (construction, agricultural work, urban air pollution), when a significant lifestyle change like rapid weight loss has temporarily increased your toxic load, or when liver function tests show your detox systems are under strain

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