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Here is what the evidence actually shows

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suggested that thiol-based catalysis is prone to overoxidation, whereas selenol-based catalysis is resistant to overoxidation [39]

NAC: How They Differ While both NAD and NAC play key roles in supporting cellular health, they work through different mechanisms: NAC primarily helps boost antioxidant activity by supporting glutathione production, which aids liver detoxification function, and supports respiratory health. NAD helps power your body at a cellular level by supporting energy production, mitochondrial function, and cellular processes linked to healthy aging. Depending on your wellness goals, you might choose one or take both for complementary support

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