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Lenses collected for western blot analysis were homogenised in homogenising solution and then stored at -80C

This response involves three primary pathways: PKR-like ER kinase (PERK), inositol-requiring enzyme 1 alpha (IRE1), and activating transcription factor 6 (ATF6), all of which are activated under conditions of ER stress [49]

Available at: Nordqvist, J

inhibition of GSK-3 upon phosphorylation occurs because the modified N-terminal region acts as a pseudo-substrate and competes for binding with primed substrates [296]

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