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Description
Sexually mature males only produce GnRH pulses (Figure 4), while females generate GnRH pulses and also trigger a GnRH surge during proestrus of the ovulatory cycle (Cooper et al., 2025)

Yet, individuals with pre-existing conditions may be at increased risk of serious adverse effects (including death) if one considers the possibility that large doses of supplemental vitamin E might interfere with medications, and possibly lower their efficacy or increase their toxicity (1)

Thus, it was suggested that the SMARCB1 deficiency contributed to the eprenetapopt sensitivity to SMARCB1-deficient cell lines

Control Release 113 (3), 189207

J.MattarP.et al (2021)