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It also inhibits NF-B p65 nuclear translocation, reducing COX-2 and IL-6 expression, thereby mitigating oxidative and inflammatory damage at multiple targets (46)

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This adhesive property further promotes the absorption of drugs and peptides, optimizing treatment outcomes

155 Additionally, aspirin inhibits metastasis in Lewis lung carcinoma cells and acts as a negative regulator of epithelial-to-mesenchymal transition (EMT) in oncogenic K-RAS-expressing NSCLC cells by downregulating Slug and upregulating E-cadherin