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Vial Design: Each vial is designed with a gas-tight, sterilised clear structure, sealed with a pre-sterilised rubber septum by gamma-irradiation, and a centre tear-out crimp seal to maintain sterility

VIP delivery challenges The main limitation of VIP as a therapeutic peptide is its extremely short plasma half-life

These receptors predominate on differentiated mature adipocytes, where they inhibit adenylyl cyclase activity and suppress lipolysis (12)

Possible causes: dead space accumulation (discussed above), inaccurate water volume at reconstitution (more water means more dilute, means more volume per dose, means fewer doses from the same amount of peptide), or air in the vial displacing solution