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Histone acetylation and methylation are the most intensively investigated modifications of histone covalent modifications

4,74-76 Cancer

Knowing these risk factors helps in diagnosing and managing CVS early

Several recent studies also point to the importance of the ECM in facilitating metastatic tumour cell growth in the metastatic niche (BOX 3)

J Cereb Blood Flow Metab 39: 16691677, 2019
