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The elimination of ROS by scavenging enzymes or increased ROS production may be effective options for cancer therapies [12]

J Biol Chem 274:636673 Chae HZ, Kang SW, Rhee SG (1999) Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin

Gsh-triggered release of sulfur dioxide gas to regulate redox balance for enhanced photodynamic therapy

as well as (3) current attempts in targeting the IGF-1R as a potential option in cancer therapy
The classic clinical sign is leukocoria (an abnormal white pupillary reflex), often accompanied by strabismus
