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doi: 10.1097/FTD.0000000000000525
3c,d, AC3-C cells exposed to IL-1 presented a higher number of NSE compared with the same cell type under control condition
N.et al (2020)
All these directly or indirectly indicates that ROS play an important role in CP fibrosis ( Figure 3B )
Interestingly, the NCT00071799 study reported that MDS patients treated with 5-Aza (75 mg/m 2 subcutaneously) + BSC exhibited prolonged hematological responses and increased RBC IT compared to those receiving standard chemotherapy (cytarabine + anthracycline) + BSC (median OS: 24.5 months vs 16 months) [346,347,348,349,350]
