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doi: 10.3389/fcell.2021.625036 43 Mohan JeenaLKumarDRahangdaleSPratap SinghAChandra SarkhelB

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GHK-Cu stimulates angiogenesis primarily through upregulation of key growth factors including vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF/FGF-2), with research demonstrating that GHK-Cu at nanomolar concentrations increases VEGF expression in dermal fibroblasts and stimulates human umbilical vein endothelial cell (HUVEC) proliferation through enhanced VEGF and FGF-2 expression

It is essential for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis

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