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[DOI] [PubMed] [Google Scholar] 180.Sohn J, Rudolph J

5-Amino-1MQ is an orally bioavailable, cell-permeable small molecule that potently inhibits NNMT (nicotinamide N-methyltransferase), the enzyme responsible for methylating nicotinamide to 1-methylnicotinamide (1-MNA)

Protein expressions were normalized to beta-Actin (Abcam)

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Elevations in HODEs and DiHOMEs induced by a 75-km bout of cycling were partially resolved in 1.5h, and fully resolved within 1d, further suggesting these compounds as markers of physiologically relevant oxidative stress