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In PMNs, the loss of the Vav GEF family member Vav3 abrogates ROS production (Utomo et al., 2006), as Vav is required for both the activation of Rac2 and the phosphorylation of p40 phox (Kim and Dinauer, 2001

The Glyoxalase System The glyoxalase system, a molecular maestro found in the cellular orchestra, orchestrates its performance in every mammalian cells cytoplasm and occasionally takes a bow in the nucleus of some cells [1]

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

doi: 10.1038/s41598-023-28956-8

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