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Description
Due to the risk of hypoglycemia, the initial treatment doses of insulin administered simultaneously with pramlintide must be lowered by 50% or more [59]
The World Anti-Doping Agency
10.1042/CS20150502 [DOI] [PubMed] [Google Scholar] Galluzzi L., Bravo-San Pedro J
PMID 18020969
This will allow the selective and effective localization of drugs at predefined targets (e.g., overexpressed receptors in cancer) while restricting its access to normal cell thus maximizing therapeutic index and reducing toxicity
