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Reverse electron transport (RET) drives electrons from complex II to I via CoQ, reducing NAD + to NADH and increasing NADH/NAD + ratios (Kowalczyk et al., 2021)

Contextual Variables Published dosing patterns are influenced by factors such as: body weight of the research model species differences (rodent vs in-vitro systems) delivery method measurement endpoints (angiogenesis, fibroblast activity, inflammation markers, etc.) These variables limit direct comparison between studies

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[9] With the standard regimen, we do not expect any liver issues or nerve issues