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4j and Extended Data Fig

125 Bacterial or viral infection is a common trigger for COPD exacerbations, and exposure to LPS induces p38MAPK activation in rat peritoneal macrophages and dendritic cells as well as an increase expression of inflammatory mediators

Rosenkranz, S., Howard, L

Fluorescein-labeled D-R6 translocates into the rat ileal membranes via energy-dependent pathway, involving electrostatic interactions between anionic proteoglycans in membrane and cationic D-R6 peptide

This includes supporting vascular function and tissue repair signals-factors that play indirect roles in managing inflammatory loads in the body