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It is an anti-ulcer peptide (9-12), interacting with NO-system (13), and, unlike other peptides, it is particularly stable in gastric juice (14) and is used consistently without a carrier (9-11, 13-24), being safe in patients with the inflammatory bowel disease (coded PL-10, PLD 116, PL 14736) (21)

The Bradford assay was used to determine protein concentration of cell extracts, from there samples with the same amount of protein were separated using SDS-PAGE technology and transferred onto a PVDF membrane

Furthermore, human studies showed that exercise increased MOTS-c levels in skeletal muscle and blood circulation, indicating that MOTS-c is a mitochondrial-derived peptide induced by skeletal muscle exercise (9, 10)

44 The controlled release of drugs from microspheres depends on the rate of degradation and is regulated by the internal monomer ratio or molecular weight

Alternatively, it is also available as a dietary supplement and as a prescription medication