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For example, TNF is responsible for the removal of claudin-1 from tight junctions

It counteracts the poisonous effects of acetaldehyde turning it into acetic acid

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[DOI] [Google Scholar] 47.Tanner E.E.L., Curreri A.M., Balkaran J.P.R., Selig-Wober N.C., Yang A.B., Kendig C., Fluhr M.P., Kim N., Mitragotri S