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Studies have shown that ID weakens the response to these therapies, making patients more susceptible to complications such as fatigue, immunosuppression, and anemia

Concurrently, oxidative stress is significantly increased during inflammation, and upregulated NOX1 expression in microglia increases reactive oxygen species (ROS) levels, thereby exacerbating glutamate neurotoxicity and ultimately worsening neuronal damage [300, 301, 309]

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Very common (more than 1 in 10 people): mild injection-site pain or redness that eases within a day

At 150 keV, the tumor region exhibited a high CT signal, with a recorded CT value of 368.66 HU, and this elevated signal intensity was maintained as the X-ray energy increased (Figure S5B)