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In particular, we have developed and tested preclinical compounds, such as INF-4E, INF195, and INF200, which reduce NLRP3 activation, improve post-ischemic cardiac function, and decrease infarct size [59, 60, 145]

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Mitochondrial management of reactive oxygen species

[9] Deep intramuscular administration into the gluteal muscle using a 22-gauge needle is recommended, and patients who self-inject must be trained in aseptic technique, site rotation and safe sharps disposal to reduce infection and tissue-injury risk