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Trigger point injections provide instant relief

Faster Efficacy: Effects can be felt more quickly than oral supplements, which require digestion

Common side effects include: Injection site reactions pain, redness, or swelling at the injection site Mild diarrhoea or gastrointestinal upset usually transient Skin reactions itching or rash (uncommon) Hypokalaemia rare, occurring when severe megaloblastic anaemia is corrected rapidly Serious adverse effects are extremely rare but may include anaphylaxis in hypersensitive individuals

oral administration of FA (500 g/day) was continued from 7 days before the first dose of pemetrexed until 21 days after the last dose of pemetrexed, whereas 1000 g B12 was administered intramuscularly, 1 week before the first dose of pemetrexed and every three cycles thereafter

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