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Remaining amounts of non-glutathionylated apocarotenoids were determined by HPLC, using a Shimadzu HPLC system with a C18 column (Hypersil Gold C18, 150 4.6 mm, 5 m) and the mobile phases A: acetonitrile with 0.1% (v/v) formic acid and B: water with 0.1% (v/v) formic acid and a column temperature of 40 C

Step 4: Monitor bloodwork every 8 to 12 weeks

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In silico studies further predicted NF-B as a principal target of EGCG, suggesting that its anti-inflammatory effects may be mediated through suppression of NF-B activation and downstream cytokine production (66)

The present review has highlighted the significance of natural compounds, including plant extracts, essential oils, nutraceuticals, and phytochemicals, in offering protective, therapeutic, preventive, and ameliorative effects on colonic inflammation