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1 OA pathogenesis appears to be closely linked to exasperated oxidative stress and the overproduction of reactive oxygen species (ROS)

doi: 10.3390/nu10111723 51 KordyKGaufinTMwangiMLiFCeriniCLeeDJet al

During AD, the phosphorylation of Tau can occur on the numerous serine, threonine and tyrosine residues of the protein, the progressive phosphorylation of which correlates with the Braak Stages of AD pathology and can take place in over 40 sites (Neddens et al., 2018

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