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Reliable imaging tools such as magnetic resonance spectroscopy (MRS) now allow real-time measurement of brain GSH levels, facilitating early detection and therapeutic monitoring

NAC did not enhance GSH nor cysteine in venous cord blood, possibly due to either adequate maternal GSH levels at enrollment, or to an effect too transient to be detected at time of delivery

[21] [22] Clinical significance [edit] Patients with mutations in the GSS gene develop glutathione synthetase (GSS) deficiency, an autosomal recessive disorder

It has been found that cancer-associated fibroblasts (CAFs) have a greater dependence on Gln than tumor cells do and exhibit greater sensitivity to GLS inhibition (51)

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