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Risks and Side Effects While generally safe, vitamin B12 injections can have side effects or risks, such as: Mild pain, swelling, or redness at the injection site Dizziness, headache, or nausea Allergic reactions (rare) Hypokalemia (low potassium levels) in individuals with severe deficiency undergoing treatment People with allergies to cobalt or who have Lebers disease should avoid B12 injections unless specifically advised by a doctor

Standard maintenance therapy for pernicious anaemia involves injections every 2 to 3 months following an initial loading phase of six injections over two weeks

Beyond this window, degradation accelerates even under refrigeration

2025 [cited 3rd June 2025] CDSCO [Internet]

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