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Interestingly, ERK1/2 signaling plays an important role in memory formation and retrieval [125], and brains exposed to the A peptide have decreased activation of ERK1/2 due, in part, to a deficiency in protein kinase C II (PKC II)-mediated signaling [124]
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Witschi, A., et al
It activates all three receptors: GLP-1, GIP, and the glucagon receptor
