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Intradiscal injection of TNF or NGF in combination with vascular endothelial growth factor (VEGF) immediately after IVD injury induction has shown to accelerate pain behavior in rats
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In the region of the titration curve at the upper right, after the midpoint, the acidbase properties of the solution are dominated by the equilibrium for reaction of the conjugate base of the weak acid with water, corresponding to K b
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