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In this advanced disease stage, vascular density was quantified as a combined all-layer metric due to limited anatomical separation of individual plexuses

demonstrated that a marked increase in the expression of p62, LC3, and Beclin-1 was related with radiation therapy in glioblastoma biopsy samples, whereas LC3 and p62 expression was associated with a poorer overall survival, and LC3 was associated with the methylation in the promoter of O 6 -methylyguanine-DNA methyltransferase (MGMT) and telomerase reverse transcriptase (TERT)