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This, combined with reduced antioxidants such as glutathione and glutathione peroxidase (GPx), increases granulosa cell susceptibility to ferroptosisan iron- and reactive oxygen species (ROS)-dependent programmed cell deathultimately impairing oocyte maturation and competence

By contrast, BPC 157 largely interacts with the NO system in various models and species, as shown in cytoprotection studies, in particular, studies using both L-NAME and L-arginine as individual agents or in combination[2-4]

For instance, it has been suggested that tetracycline antibiotics might represent an attractive therapeutic alternative for different psychiatric disorders [315]

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