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doi: 10.1186/s13075-017-1418-6

In each of the apo trajectories, one monomer has a perfectly folded site, another a partially folded, and the last is fully unfolded (Fig

Furthermore, unlike in experiments using animals, clinical studies usually involve patients with heterogeneous backgrounds, different ages, sexes, and sensitivity to stress

When this transporter is underexpressed due to the S allele, SSRIs face a functional ceiling effecttheir capacity to further elevate extracellular serotonin is reduced, leading to incomplete receptor stimulation and, therefore, suboptimal antidepressant efficacy (Porcelli et al., 2012)

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