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Engrailed-2 is another transcription factor that influences several biological processes implicated in ASD, as Engrailed-2 is located in the ASD-susceptibility region on the human chromosome [165,166,167]
Le Trant N, Meshnick SR, Kitchener K, et al
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Thus, we identified a cell death checkpoint that depends on the non-metabolic function of HK2 in TNF-induced RIPK1-mediated cell death, revealing a potential therapeutic avenue for RIPK1-related diseases through HK2 non-metabolic functions
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