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The availability of carnitine in skeletal muscle appears to influence the fuel choice during exercise [274]

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This may in part be because gut bacteria metabolise l-carnitine into a compound called trimethylamine-N-oxide (TMAO), which is known to cause furring of the arteries and potentially lead to atherosclerosis Thyroid function: taking l-carnitine as a supplement can make the symptoms of a low-functioning thyroid worse Muscle weakness and seizures: high amounts of l-carnitine may cause muscle weakness in those with chronic kidney disease and may increase the risk of seizures in those with seizure-related disorders Food sources of carnitine There are many natural food sources of carnitine

ALC should not cause any anxiety or depressive effects

The positive ratio of -6/-3 PUFA, vitamins (E, B, C, and -carotene), fibers, minerals (selenium, iron, zinc, iodine) are key components of the MeD and account for its beneficial effects [15, 62, 121, 186]