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In addition to p38 MAPK and ERK, c-KIT activation is associated with the phosphoinositide 3-kinase (PI3K) signaling pathway, which not only regulates cell survival but also causes pigmentation by activating the serine/threonine-specific protein kinase AKT

HLRCC syndrome is caused by an autosomal dominantly inherited mutation of the fumarate hydratase ( FH ) gene (Tomlinson et al., 2002)

glutamicum strains CYS- 2/pECt-Mb_egtB-Ms_egtDE produced EGT at 100 mg/L in 120 h of fed-batch cultivation in flasks using a semisynthetic medium containing 10 g/L yeast extract as a starting medium (Hirasawa et al

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