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As a result, enhancements in glucose homeostasis could be due to one or both of such effects 24,25 .In aquaculture, tilapia ranks as the second most important finfish species cultivated globally, with Nile tilapia ( Oreochromis niloticus ) being the predominant variety in worldwide production 26 , furthermore, it is estimated that by 2030, it will account for 62% of the total worldwide aquaculture production 27

Additionally, genetic factors, such as polymorphisms in the FMO3 enzyme responsible for converting TMA to TMAO, may further amplify these differences

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