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In contrast, strep-MBP-ROXY9 and its CPYC and CCLS variants were inactive

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ATG8-defective mice accumulate SQSTM1, resulting in the hyperactivation of NRF2 and limiting oxidative stress [119], whereas Nrf2 - knockout mice exhibit elevated oxidative stress [120]

Additionally, this research was supported by the National Center for Complementary and Integrative Health and Office of the Director of the National Institutes of Health under award number 1R21AT011371-01A1 to Dr