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480 Further innovations include Angiopep LipoPCB nanoparticles and poly(L-malic acid)-based nanoscale immunoconjugates, which have demonstrated enhanced BBB penetration and immune modulation

doi: 10.1111/j.1742-1241.2010.02506.x

Furthermore, the role of luminal microbes in SLE development is reinforced by the fact that patients express the LTA receptor, TLR2, in greater abundance when compared to healthy controls, and the removal of commensal microbes via antibiotic treatment can ameliorate disease symptoms (Liu et al

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[DOI] [PubMed] [Google Scholar] Fernandez N, Gottardo FL, Alonso MN, Monczor F, Shayo C, Davio C