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Four -ketoacid dehydrogenase complexes ( Figure 4 ), including: (i) the pyruvate dehydrogenase complex that catalyzes the conversion of pyruvate to acetyl-coenzyme A (CoA), an important substrate for energy production via the citric acid cycle

Hirata et al (126) developed hybrid molecules that combine the oxidized indole structure of neuroprotective agents with the polyphenolic structure of curcumin, applying them to mouse hippocampal HT22 cells
