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Under resting conditions, ASC is S-glutathionylated (notably at Cys171), a modification that impairs ASC oligomerization and prevents spontaneous inflammasome formation 67

Depending on the patients needs, both oral and intravenous administration of ALA is commonly recommended in order to achieve therapeutic levels in the body

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The glutamate hypothesis of schizophrenia is based on the association of the disorder with NDMA receptor hypofunction and the overlap in clinical presentation with NMDA encephalitis (Howes et al., 2015)

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